- Medical Science Paper I: Section A
- Medical Science Paper 1: Section B
- Medical Science Paper II: Section A
- Medical Science Paper 2: Section B
Q- 1(a) Describe the shoulder joint under the following heads. [2.5*4 =10]
- Applied anatomy
Q-1 (b) Describe the thyroid gland under the following heads. 
- Surgical anatomy
Q-1 (c) Define synapse, enumerate the steps of synaptic transmission. What is the significance of synaptic delay ? 
Q-1 (d) What is the mechanism of accommodation in eye ? Why near point recedes in old age ? [5 + 5 = 10]
Q-1 (e) Avidin, an egg protein has great affinity for a vitamin. Discuss the biochemical role of that vitamin. 
Q-2 (a) Describe the morphological relations of Kidney. Add a note on relations of right Kidney. [5 + 5 = 10]
Q-2 (b) Describe the steps in development of uterus. Name any four congenital malformations of uterus. [6 + 4 = 10]
Q-2 (c) Define a dermatome. Illustrate by means of labelled diagram(s) dermatomes of lower limb. 
Q-2 (d) Name the functions of placenta. List any four malformations of placenta. 
Q-2 (e) Describe the structures forming the floor of fourth ventricle of brain. 
Q-3 (a) Enumerate the factors required for normal erythropoiesis. Why polycythemia occurs at high altitude ? [10 +5=15]
Q-3 (b) Describe the role of baroreceptors in regulation of normal B.P . Why is it effective only in short term regulation of Blood Pressure ( B.P) ? [10 + 5=15]
Q-3 (c) Describe the physiological basis of signs and symptoms of insulin deficiency. Explain the saying, starvation in the midst of plenty. [ 15 + 5= 20]
Q-4 (a) Name the folate antagonists used in treatment of bacterial infections and malignancy. Discuss their mechanism of actions also. 
Q-4 (b) Which mineral irreversibly inhibits glycolysis ? Discuss clinical manifestations due to its deficiency and toxicity. 
Q-4 (c) Write in brief- [5 + 5 = 10]
- Reverse transcriptase- P.C.R.
- Significance of S. enzymes in liver diseases
Q-5 (a) Discuss differentiating features of primary and metastatic malignancies. 
Q-5 (b) Briefly describe various cells of immune system. Discuss classification system to differentiate lymphocytes. 
Q-5 (c) Explain why ?
- Aspirin should not be administered around full- term pregnancy period
- Thiazide diuretics alone are first line drugs for treating mild (stage-1) Hypertension and also potentiate other antihypertensive drug’s effect when used in combination with them to treat stage II & III hypertension.[2.5]
- Low molecular weight heparin(LMWH) are preferred over conventional heparin for anticoagulant indication. [2.5]
- Metformin is a first line orally effective drug for treating Type-II diabetes mellitus. [2.5]
Q-5 (d) Describe different types of injuries sustained by a victim of gang rape. How will you proceed to examine and opine in such a situation? 
Q-5 (e) Discuss role of mediators in different reactions of inflammation.
Q-6 (a) Discuss pathogenesis of oral cancer. Briefly describe the malignant lesions that are likely to affect oral cavity. 
Q-6 (b) Describe aetiopathogenesis of alcoholic cirrhosis. Describe the gross and microscopic appearance. 
- Discuss pathogenicity and laboratory diagnosis of Amoebiasis. 
- Discuss pathogenicity and laboratory diagnosis of Herpes simplex virus 
Q-7 (a) Discuss morphology, pathogenicity and laboratory diagnosis of Candidiasis. 
- Discuss the pharmacological strategies available for post myocardial infarction. [7.5]
- Discuss the first line antimycobacterial drugs with special reference to their mechanism of action, side effects and development of resistance. [7.5]
Q-7 (c) What are the possible contributing factors in pathogenesis of carcinoma breast? Describe briefly histopathology of different types of breast carcinoma. 
Q-8 (a) Enumerate the drugs of abuse among young population of India. Describe the long term effects of drug abuse on health and personality of drug abuser. 
Q-8 (b) What are various tests to detect semen? Describe the confirmatory tests for semen stains. 
Q-8 (c) Enumerate the injuries caused by sharp weapon. Describe how you will correlate the weapon of offence with injuries. 
Q-1 (a) A 45 year old lady after the death of his husband 2 months back, is feeling lonely and remains aloof. [3+7=10]
- Enumerate the likely conditions.
- How will you diagnose and manage a major depressive disorder ?
Q-1 (b) What is the principle of ultrasound? In which medical conditions, it is almost diagnostic?[3+7=10]
Q-1 (c) A 2 year old boy was brought to you with cough and fever for 3 days. On examination the respiratory rate was 46 per minute along with lower chest indrawing.
- Classify the illness of this child as per IMNCI
- Outline the treatment of this child.
- Enumerate the general danger signs you will ask or look for in this child to assess the severity of illness. [2+4+4=10]
Q-1 (d) An 8 month old child, weighing 8 kg, is brought with loose motions 6 per day, mixed with blood, for last 2 days. There is no history of vomiting.
- Enumerate the 4 most important signs you will look/feel for to assess the severity of dehydration.
- Assessment of dehydration reveals SOME dehydration. Write the initial prescription for appropriate management of this child.[4+6=10]
Q-1 (e) How will you differentiate between irritant and contact dermatitis? Write the salient differentiating points of both. 
Q-2 (a) An 18 year old boy was brought to the casualty in stuporose condition with history of high grade fever since last 3 days.
- Enumerate the causes
- Describe the management of cerebral malaria. [10+15]
Q-2 (b) An 18 month old girl is diagnosed with Severe Acute Malnutrition (SAM). Outline the 4 diagnostic criteria for this condition. Write the 10 steps for appropriate management of severe malnutrition as per WHO guidelines. [5+10]
- Enumerate the cutaneous, mucosal, follicular and nail manifestations of Lichen Planus.
- Describe the histopathological features of lichen planus and their relevance to clinical presentation. [6+4]
Q-3 (a) An elderly woman is bed ridden for 4 weeks because of a fractured hip. She is brought to the casualty with sudden onset of breathlessness.
- Enumerate the possible causes of breathlessness in this case.
- Describe the management of acute pulmonary embolism. [5+20]
Q-3 (b) A 3 year child was brought to you with history of cyanotic spells and exertional dyspnea. The symptoms were relieved on assuming a knee chest position. The child had central cyanosis and clubbing. There were no features suggestive of congestive heart failure. Heart size was normal.
- What is the most probable diagnosis ?
- What is the major pathophysiological abnormality ?
- Describe the pathophysiology and management of cyanotic spells in this condition. [2+3+10=15]
- What are the various etiological factors for causation of vitiligo?
- Enumerate various disorders associated with vitiligo? [6+4=10]
Q-4 (a) A 50 year old male, chronic heavy alcoholic for 20 years, was administered aspirin for headache. Following which he developed sudden massive hematemesis.
- Enumerate the causes of hematemesis in this case.
- How will you manage this patient ? [10+15]
- Draw a flow diagram of pathophysiology of Respiratory Distress Syndrome in new born.
- Outline the measures to prevent RDS in pregnant woman at 30 weeks of gestation, with threatened preterm labour.
- Enumerate the clinical factors predisposing to billirubin toxicity in new born infants. [ 5 + 5 + 5 =15]
Q-4 (c) A child in 2nd class of public school had an itchy skin lesion. Within next 1 month, this lesion spread to 10 other students in the same class. Examination revealed multiple excoriated papulovesicular itchy lesions in finger webs and flexural aspects of wrists.
- What is the most likely diagnosis ?
- Outline the prophylactic measures to be undertaken to prevent the spread to other children.
- Outline the management of individual children in this class. [2+4+4]
Q-5 (a) What are the advantages and limitations of minimally invasive surgery? Briefly enumerate the principles of laparoscopic cholecystectomy and the complications which can occur during the procedure.[4+6]
Q-5 (b) What are the mode of infection, clinical presentation and complications of amoebic liver abscess? Briefly outline the management of patients with amoebic liver abscess including surgical intervention. [2+5+3]
Q-5 (c) Define menopause. What are the signs and symptoms of menopause ? How will you treat a case of hot flushes in a postmenopausal woman ? [2+5+3]
Q-5 (d) What are the commonly used methods of first trimester termination of pregnancy ? Enumerate the immediate and remote complications of Medical Termination of Pregnancy. [5+5]
Q-5 (e) Write a paragraph on relative and attributable risks related to disease. How do they differ in the case of heart diseases ?[6+4]
Q-6 (a) How will you calculate the expected date of delivery ? what are the methods recently used for induction of labour ? What are the indications for terminations of induction of labour ? [ 4+8+8]
Q-6 (b) What are the shortfalls in the health care delivery systems at secondary and tertiary care level ?[7+8]
Q-6 (c) what are the boundaries and parts of oral cavity? Enumerate various factors predisposing to oral cancers. Briefly enumerate the assessment and treatment of a patient with ulceroproliferative growth involving anterior 2/3 of the tongue. [4+3+8]
Q-7 (a) what are various types and causes of nipple discharge in a female? How would you examine, investigate and treat a patient with large 6 cm breast tumour with mobile axillary lymph nodes in the axilla ? [4+16]
Q-7 (b) What methods can be used for permanent sterilization of a 32 year old female having 2 children? How is laparoscopic sterilization superior to tubectomy ? [10+5]
Q-7 (c) Discuss the role of Information, Education and Communication systems (IEC) in the management of sexually transmitted diseases (STDs).[5+5+5]
Q-8 (a) What do you understand by Expanded Programme of Immunisation(EPI) ? Describe its components. [10+10]
Q-8 (b) What is the difference in clinical presentation of right and left sided colonic cancers? Enumerate various factors predisposing to colonic cancers and briefly outline the management of a patient with caecal carcinoma. [4+4+7]
Q-8 (c) Define accidental haemorrhage. How would you manage a woman at 34 weeks of pregnancy, who comes to casualty with history of painful bout of bleeding ? Mention the foetal and maternal complications associated with accidental haemorrhage. [3+6+6]
courtsey: Misfit Medico for sharing the paper.
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